Epigenetic memory over geological timescales

Abstract: I will describe our recent work examining the maintenance of DNA methylation in the yeast Cryptococcus neoformans. In many species, DNA methylation is established by a de novo enzyme that can methylate unmethylated DNA. Such enzymes act in narrow developmental windows and this initial activity is subsequently propagated epigenetically via a maintenance enzyme specific for hemimethylated DNA. I will describe a species which lacks a de novo enzyme and only harbors a maintenance enzyme.

biochemistrycancer biologychemical biologycell biologydevelopmental biologydrug discoveryevolutiongeneticsimmunologymolecular biologymicrobiologyneuroscienceplant sciencessystems biologybiotechnologybiological techniquesbiophysics

Audience: researchers in the discipline

( video )

Comments: Organizers can be contacted at m.tariq@lums.edu.pk or 22100032@lums.edu.pk for the zoom link.

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Colloquium zooming Molecular & Cellular Biology LUMS

Series comments: Zooming Molecular & Cellular Biology Colloquium was initiated on July 28th, 2020 by the Biology department at Syed Babar Ali School of Science & Engineering (SBASSE), Lahore University of Management Sciences (LUMS). The series follows through various topics which come under the ambit of Molecular and Cellular Biology and we’ve had the pleasure and honor of hosting some of the most knowledgeable scientists from around the globe. Organizers can be reached out at 24100162@lums.edu.pk or 24100001@lums.edu.pk for the Zoom link of individual talks. All lectures are LIVE streamed on SBASSE's official Facebook page.

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